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Genome-wide association study of the backfat thickness trait in two pig populations

Dandan ZHU,Xiaolei LIU,Rothschild MAX,Zhiwu ZHANG,Shuhong ZHAO,Bin FAN

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 2,   Pages 91-95 doi: 10.15302/J-FASE-2014005

Abstract: In this study, the candidate genes and genomic regions associated with the tenth rib backfat thicknesstrait were identified in two independent pig populations, using a genome-wide association study of porcine

Keywords： backfat thickness     SNP chip     genome-wide association study     compressed mixed linear model     pig    

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A post-GWAS replication study confirming the association of

Shaohua YANG,Chao QI,Yan XIE,Xiaogang CUI,Yahui GAO,Jianping JIANG,Li JIANG,Shengli ZHANG,Qin ZHANG,Dongxiao SUN

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 4,   Pages 321-330 doi: 10.15302/J-FASE-2014037

Abstract: Genome-wide association studies with an Illumina Bovine50K chip have detected 105 SNPs associated withof nine of these identified SNPs were successfully genotyped and analyzed by mass spectrometry for associationThese findings, therefore, provide strong evidence for association of variants with milk yield and

Keywords： annotation     Chinese Holstein     milk production traits     C14H8orf33 gene     single nucleotide polymorphisms     associationstudy    

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J-shaped association between dietary zinc intake and new-onset hypertension: a nationwide cohort study

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 156-164 doi: 10.1007/s11684-022-0932-3

Abstract: Overall, the association between dietary zinc intake and new-onset hypertension followed a J-shape (association between dietary zinc intake and new-onset hypertension

Keywords： dietary zinc intake     new-onset hypertension     general population     CHNS    

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U-shaped association between telomere length and esophageal squamous cell carcinoma risk: a case-controlstudy in Chinese population

Jiangbo Du,Wenjie Xue,Yong Ji,Xun Zhu,Yayun Gu,Meng Zhu,Cheng Wang,Yong Gao,Juncheng Dai,Hongxia Ma,Yue Jiang,Jiaping Chen,Zhibin Hu,Guangfu Jin,Hongbing Shen

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 478-486 doi: 10.1007/s11684-015-0420-0

Abstract: length-related single nucleotide polymorphisms (TL-SNPs) in Caucasians have been reported in genome-wide associationTherefore, we conducted a case-control study (1045 ESCC cases and 1433 controls) to evaluate the associationsMore interestingly, an evident nonlinear U-shaped association was observed between RTL and ESCC risk

Keywords： esophageal squamous cell carcinoma     telomere length     genetic variants     susceptibility     genome-wide associationstudy    

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Association between ICU quality and in-hospital mortality of V-V ECMO-supported patients—the ECMO qualityimprovement action (EQIA) study: a national cohort study in China from 2017 to 2019

Frontiers of Medicine doi: 10.1007/s11684-023-1014-x

Abstract: This cohort study was performed to explore the influence of intensive care unit (ICU) quality on in-hospitalThe study involved all V-V ECMO-supported patients in 318 of 1700 tertiary hospitals from 2017 to 2019Meanwhile, the V-V ECMO center volume was a protective factor (cutoff of ≥ 50 cases within the 3-year study

Keywords： veno-venous extracorporeal membrane oxygenation     in-hospital mortality     high-volume centers     quality control     intensive care unit capacity parameters    

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A genome-wide association study of five meat quality traits in Yorkshire pigs

Qian DONG,Huiying LIU,Xinyun LI,Wei WEI,Shuhong ZHAO,Jianhua CAO

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 2,   Pages 137-143 doi: 10.15302/J-FASE-2014014

Abstract: identify genomic regions and haplotype blocks responsible for meat quality traits in pigs, a genome-wide associationstudy was conducted for five traits including intramuscular fat content, pH at 45 min and 24 h, dripOur study added new SNP information for identification of meat quality traits in pigs and will help elucidate

Keywords： Pig     GWAS     meat quality trait     SNP    

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Association of maternal depression with dietary intake, growth, and development of preterm infants: acohort study in Beijing, China

Han Wang, Hong Zhou, Yan Zhang, Yan Wang, Jing Sun

Frontiers of Medicine 2018, Volume 12, Issue 5,   Pages 533-541 doi: 10.1007/s11684-017-0591-y

Abstract:

This study aimed to explore the association of maternal depression with nutrient intake, growth, andA cohort study of 201 infants was conducted in Beijing.

Keywords： maternal depression     preterm     infant     nutrition     growth     development    

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Genome-wide association studies: inherent limitations and future challenges

Yan Du, Jiaxin Xie, Wenjun Chang, Yifang Han, Guangwen Cao

Frontiers of Medicine 2012, Volume 6, Issue 4,   Pages 444-450 doi: 10.1007/s11684-012-0225-3

Abstract:

Genome-wide association studies (GWAS) have achieved great success in identifying genetic variants

Keywords： genome-wide association studies (GWAS)     genetic variant     cancer     limitation     challenge    

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Advancement in genetic variants conferring obesity susceptibility from genome-wide association studies

Tao Wang,Weiping Jia,Cheng Hu

Frontiers of Medicine 2015, Volume 9, Issue 2,   Pages 146-161 doi: 10.1007/s11684-014-0373-8

Abstract: The advent of genome-wide association studies (GWAS) has hastened the progress of polygenic obesity research

Keywords： obesity     genetics     genome-wide association studies     body mass index     fat mass- and obesity-associated gene    

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Genetics of ischemic and hemorrhagic stroke in Chinese population

Wei-Li ZHANG MD, PhD, Ru-Tai HUI MD, PhD,

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 21-28 doi: 10.1007/s11684-010-0013-x

Abstract: Genome-wide association (GWA) study is an unbiased and comprehensive approach to identify common riskRecently, a multistage GWA study has identified three loci on chromosomes 2q, 8q and 9p to be associatedIn this review, we mainly focus on the results from case-control association studies on genetic factors

Keywords： genetics     ischemic stroke     hemorrhagic stroke     association study    

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DQB1*060101 may contribute to susceptibility to immunoglobulin A nephropathy in southern Han Chinese

Wei Wang,Ming Li,Li Wang,Xueqing Yu

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 507-516 doi: 10.1007/s11684-016-0475-6

Abstract: Accumulating evidences have shown the ethnic-specific association between certain human leukocyte antigenThis study was designed to explore the relationship between HLA-DQB1 alleles and disease susceptibilityIn combination with our previous DRB1 results, we also analyzed the association of DRB1-DQB1 haplotypesOur study indicated that HLA-DQB1*060101 alleles may be a potential predictor of high-risk IgAN susceptibility

Keywords： DQB1     human leukocyte antigen (HLA)     IgA nephropathy     haplotype     association study    

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Survey of the Algorithms on Association Rule Mining

Bi Jianxin,Zhang Qishan

Strategic Study of CAE 2005, Volume 7, Issue 4,   Pages 88-94

Abstract:

In this paper the principle of the algorithms on association rule mining is introduced firstly, andresearches of the algorithms on association rule mining are summarized in turn according to variableAt last, some future directions on association rule generation are viewed.

Keywords： data mining     association rule     algorithms     survey    

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Obesity and overweight prevalence and its association with undiagnosed hypertension in Shanghai population

Xinjian Li, Jiying Xu, Haihong Yao, Yanfei Guo, Minna Chen, Wei Lu

Frontiers of Medicine 2012, Volume 6, Issue 3,   Pages 322-328 doi: 10.1007/s11684-012-0204-8

Abstract:

The aim of this study was to determine the prevalence of overweight and obese subjects in the Shanghaipopulation of China and its association with undiagnosed hypertension, by taking age, gender and placeMultiple logistic regression analyses were used to assess the association of overweight or obesity withThese data suggest that overweight and obesity prevalence and their association with undiagnosed hypertensionare high in our study population.

Keywords： overweight     obesity     undiagnosed hypertension     prevalence     association    

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Association study on GNB3 gene polymorphism with essential hypertension in Xinjiang Uygur group

JING Jianying, WANG Dan, WANG Xiaofeng, JIN Jianzhong, JIN Li, JIAO Yi, WEN Hao, LIN Renyong

Frontiers of Medicine 2007, Volume 1, Issue 2,   Pages 230-233 doi: 10.1007/s11684-007-0045-z

Abstract: A nested case-control study ( = 738) was carried out.Further analysis shows that there is no association between C825T genotypes and age, body mass indexNo evidence was found to suggest an association between GNB C825T polymorphism and hypertension in the

Keywords： case-control     significant difference     reaction-restriction fragment     C825T polymorphism     evidence    

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Genetic Study Identifies CBLN4 as a Novel Susceptibility Gene for Accident Proneness

Shu-lin Zhang,Hui-qing Jin,Yang Song,Wan-sheng Yu,Liang-dan Sun

Frontiers of Engineering Management 2016, Volume 3, Issue 1,   Pages 30-38 doi: 10.15302/J-FEM-2016008

Abstract: The authors performed genome-wide association study (GWAS) by 179 cases and 179 controls using the U.SThe authors then tested two independent replication sets for strong association 6 SNPs in 349 pairs of

Keywords： accident proneness     genome-wide association study (GWAS)     dopamine (DA)     ACTH     susceptibility gene     traffic    

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Title Author Date Type Operation

Genome-wide association study of the backfat thickness trait in two pig populations

Dandan ZHU,Xiaolei LIU,Rothschild MAX,Zhiwu ZHANG,Shuhong ZHAO,Bin FAN

Journal Article

A post-GWAS replication study confirming the association of

Shaohua YANG,Chao QI,Yan XIE,Xiaogang CUI,Yahui GAO,Jianping JIANG,Li JIANG,Shengli ZHANG,Qin ZHANG,Dongxiao SUN

Journal Article

J-shaped association between dietary zinc intake and new-onset hypertension: a nationwide cohort study

Journal Article

U-shaped association between telomere length and esophageal squamous cell carcinoma risk: a case-controlstudy in Chinese population

Jiangbo Du,Wenjie Xue,Yong Ji,Xun Zhu,Yayun Gu,Meng Zhu,Cheng Wang,Yong Gao,Juncheng Dai,Hongxia Ma,Yue Jiang,Jiaping Chen,Zhibin Hu,Guangfu Jin,Hongbing Shen

Journal Article

Association between ICU quality and in-hospital mortality of V-V ECMO-supported patients—the ECMO qualityimprovement action (EQIA) study: a national cohort study in China from 2017 to 2019

Journal Article

A genome-wide association study of five meat quality traits in Yorkshire pigs

Qian DONG,Huiying LIU,Xinyun LI,Wei WEI,Shuhong ZHAO,Jianhua CAO

Journal Article

Association of maternal depression with dietary intake, growth, and development of preterm infants: acohort study in Beijing, China

Han Wang, Hong Zhou, Yan Zhang, Yan Wang, Jing Sun

Journal Article

Genome-wide association studies: inherent limitations and future challenges

Yan Du, Jiaxin Xie, Wenjun Chang, Yifang Han, Guangwen Cao

Journal Article

Advancement in genetic variants conferring obesity susceptibility from genome-wide association studies

Tao Wang,Weiping Jia,Cheng Hu

Journal Article

Genetics of ischemic and hemorrhagic stroke in Chinese population

Wei-Li ZHANG MD, PhD, Ru-Tai HUI MD, PhD,

Journal Article

DQB1*060101 may contribute to susceptibility to immunoglobulin A nephropathy in southern Han Chinese

Wei Wang,Ming Li,Li Wang,Xueqing Yu

Journal Article

Survey of the Algorithms on Association Rule Mining

Bi Jianxin,Zhang Qishan

Journal Article

Obesity and overweight prevalence and its association with undiagnosed hypertension in Shanghai population

Xinjian Li, Jiying Xu, Haihong Yao, Yanfei Guo, Minna Chen, Wei Lu

Journal Article

Association study on GNB3 gene polymorphism with essential hypertension in Xinjiang Uygur group

JING Jianying, WANG Dan, WANG Xiaofeng, JIN Jianzhong, JIN Li, JIAO Yi, WEN Hao, LIN Renyong

Journal Article

Genetic Study Identifies CBLN4 as a Novel Susceptibility Gene for Accident Proneness

Shu-lin Zhang,Hui-qing Jin,Yang Song,Wan-sheng Yu,Liang-dan Sun

Journal Article